The study you mentioned, titled "Proatherogenic immune responses are regulated by the PD-1/PD-L pathway in mice," was conducted by Gotsman et al. and published in the Journal of Clinical Investigation in 2007.
In this study, the researchers aimed to investigate the role of the PD-1/PD-L pathway in regulating immune responses associated with atherosclerosis, a chronic inflammatory disease characterized by the formation of plaques in the arterial walls. The PD-1/PD-L pathway is a regulatory mechanism involved in immune system modulation, particularly in preventing excessive immune activation and maintaining immune homeostasis. PD-1 (programmed cell death protein 1) is a cell surface receptor expressed on immune cells, while PD-L (programmed death-ligand) molecules are expressed on antigen-presenting cells and other cell types. The interaction between PD-1 and PD-L molecules inhibits immune responses and helps prevent tissue damage caused by excessive inflammation.
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Explain the negative impact of deforestation, and also 2 ways Humans have made efforts to protect our planet's forestland in a short paragraph (4 or more sentences).
Answer:
See below.
Explanation:
Deforestation, the process of cutting down and clearing forests for other land uses, has numerous negative impacts on the environment. It contributes to climate change by releasing large amounts of carbon dioxide into the atmosphere, as trees absorb carbon dioxide and produce oxygen. Deforestation also leads to soil erosion, loss of biodiversity, and increased frequency and severity of natural disasters like floods and landslides. Additionally, deforestation destroys the habitats of countless species, which can lead to their extinction.
Fortunately, humans have taken steps to protect our planet's forestland. One way is through reforestation efforts, which involve planting new trees in areas where forests have been cleared. Another way is through conservation, which involves protecting existing forests and preventing further deforestation. Governments and environmental organizations have established protected areas and implemented policies and regulations to limit deforestation and promote sustainable land use practices. Additionally, there is a growing movement to promote the use of sustainable products, like recycled paper and wood products from sustainably managed forests, which can help reduce the demand for new products that contribute to deforestation.
A student builds a plant cell model by arranging different foods in a bowl. In this cell model, what do the different pieces of food represent?
A.substances that the cell consumes
B.structures that perform different cell activities
C.tissues that are formed by different cells
D.configuration of parts during cell division
Answer:
its a thing
Explanation:
The study of the cell is called cell biology.
The correct answer to the question is option B that is structures that perform different cell activities
What is Cell division?The formation of a new cell from the old cell is called cell division.
According to the question, the different food particles represent the cell organelles that perform the cell's different activities.
Hence, the correct answer to the question is option B.
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Please help me to elaborate this question.
How did History and Philosophy of Science (HPS) minimize the "fragmented" learning of the energy concept based on the empirical results?
HPS provided a holistic approach to studying the energy concept by integrating historical and philosophical perspectives, overcoming fragmented learning.
The history and philosophy of science (HPS) has played a crucial role in minimizing the fragmented learning of the energy concept by providing a holistic approach to its study. Traditionally, the teaching of energy in science classrooms has often focused solely on empirical results and mathematical equations, neglecting the historical and philosophical dimensions that surround the concept.
By incorporating HPS into the study of energy, students gain a deeper understanding of its development over time, the societal and cultural influences that shaped its understanding, and the philosophical underpinnings that guide its use and interpretation. This approach helps students see energy as more than just a mathematical formula or a set of isolated phenomena.
By examining the historical context, students can appreciate the gradual evolution of the energy concept, the controversies and debates that arose, and the scientific advancements that led to our current understanding.
By integrating historical and philosophical perspectives, HPS minimizes the fragmented learning of energy by offering a comprehensive understanding of the concept, enabling students to see its interconnectedness with other scientific ideas and its relevance to broader human knowledge and inquiry.
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Question: What are the effects of fishing on the reef ecosystem?
Answer:
Additionally, certain types of fishing gear can inflict serious physical damage to coral reefs, sea grass beds, and other important marine habitats. Coral reef fisheries, though often relatively small in scale, may have disproportionately large impacts on the ecosystem if conducted unsustainable.
Explanation:
Explanation:
Additionally, certain types of fishing gear can inflict serious physical damage to coral reefs, seagrass beds, and other important marine habitats. Coral reef fisheries, though often relatively small in scale, may have disproportionately large impacts on the ecosystem if conducted unsustainably.
Which two words describe the grass in this food chain?
A. Autotroph, primary consumer
B. Heterotroph, producer
C. Heterotroph, primary consumer
D. Autotroph, producer
Answer: Autotroph, producer
Explanation: The grass gets eaten by primary consumer starting the food chain
In a food chain, the grass is referred to as an autotroph and producer. Therefore, option D is correct.
What are autotrophs?An organism is referred to as an autotroph or primary producer when it uses carbon from simple substances like carbon dioxide to create complex organic compounds. These creatures often obtain their energy from inorganic chemical reactions or light.
Both plants like blue-green algae and microorganisms like cyanobacteria are assumed to be autotrophs. Most plants are autotrophs because they create their own food through photosynthesis. But there are always exceptions to the norm. Some plants are parasitic and non-photosynthetic, getting their nutrition from a host.
Thus, the grass in a food chain is described as autotroph and producer. Therefore, option D is correct.
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Which of the following statements about the chart is true?
90% of children can produce /k/ correctly at the age of 2 years.
About half of children can produce /v/ correctly at the age of 4 years.
About half of children can produce /r/ correctly at the age of 8 years.
100% of children can produce /w/ correctly at the age of 3 years.
The true statement about the chart is:
About half of children can produce /v/ correctly at the age of 4 years.
PLS HELP What are three types of natural selection that act on variation?
A) Stabilizing, directional, and disruptive
B) Physical, chemical, and organic
C) Genetic, hereditary, and environmental
D) None of the above
Stabilizing selection, directional selection and disruptive selection are the three types of natural selection.
What are these types of selection?
Natural selection is the process wherein organisms get better adapted to their environments and tend to survive and produce more offsprings. It is basically a mechanism of evolution which favors those organisms that can better adapt to their environment.
Directional selection: this theory states that an extreme phenotype (a characteristic or trait) is favored over other phenotypes and this causes the allele frequency to shift in favor of the extreme phenotype over time. A particular trait, if favorable, will be expressed in the population at the most beneficial frequency.
Stabilizing selection: in this type, meaning a non-extreme trait is favored instead of one of the two extreme traits. Stabilizing selection is said to be the most common mechanism for natural selection, because most traits do not change drastically over time.
Disruptive selection: This selection is bimodal. It favors both of the extreme traits in a population.
So therefore, stabilizing selection, directional selection and disruptive selection are the three types of natural selection.
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In the origin of the cell, why would the formation of a simple lipid bilayer membrane not be sufficient? & what else would have to be apart of such membrane?
The formation of a simple lipid bilayer membrane would not be sufficient for the origin of the cell because a cell requires more than just a physical barrier to separate itself from the environment. While a lipid bilayer can provide a basic barrier to separate the internal and external environments, it cannot perform essential functions required for cellular life.
For instance, in order for a cell to survive, it needs to have the ability to maintain a stable internal environment, a process known as homeostasis. A lipid bilayer alone cannot regulate the flow of molecules and ions across the membrane to maintain a stable internal environment. Therefore, the membrane would need to have specialized proteins that allow for the selective transport of molecules and ions in and out of the cell.
Additionally, a lipid bilayer alone cannot carry out metabolic reactions required for cellular functions. Enzymes and other proteins are required for cellular metabolism, which would need to be present within or attached to the membrane.
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Match the pollutant to the water pollution classification
Top
1. Heat
2. Parasitic worm
3. Animal feces
4. Household cleaners (drain-O and bleach)
5. Light fluid
6. Arsenic
A. Inorganic chemical
B. Physical agent
C. Heavy metal
D. Organic matter
E. Organic chemical
F. Pathogen.
(Example on how to answer=
1. Baby belongs to, F. Couch.).
ater pollutants can be classified as organic pollutants, inorganic pollutants, pathogens, suspended solids, nutrients and agriculture pollutants, thermal, radioactive, and other pollutants.
Answer:
1- Heat -- B. Physical agent
2- Parasitic worm -- F. Pathogen
3- Animal feces -- D. Organic matter
4- Household cleaners (drain-O and bleach) -- E. Organic chemical
5- Light fluid -- D. Organic matter
6- Arsenic -- C. Heavy metal
On what factors does numbers of sweaters a factory owner produces depend?
They are employed in the creation of goods and services. Land, labor, capital, and entrepreneurship are the four categories of components of factory production that economics distinguish between.
What are the four production factors used for?The factors of production are the resources needed to produce a good or service in order to earn money. The four elements of production are land, labor, capital, and entrepreneurialism, according to economists. An economy could be said to be built on them.
What are the four production factors?Land, labor, capital, and entrepreneurship are the four categories into which economists generally divide the components of production. Natural resources are referred to as "land," "labor" is defined as "work effort,” and "capital" is everything created that is used to create anything else.
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SPEED 8. European moles and Sumatran tigers both have eyes. However, European moles live completely in the dark and have very small eyes, while Sumatran tigers have large eyes that can see prey from far away. What most likely explains why both European moles and Sumatran tigers have eyes and why their eyes are different?
Answer:
What most likely explains why both European moles and Sumatran tigers have eyes and why their eyes are different? European moles and Sumatran tigers both have eyes. However, European moles live completely in the dark and have very small eyes, while Sumatran tigers have large eyes that can see prey from far away.
Explanation:
European moles live completely in the dark and have very small eyes, while Sumatran tigers have large eyes that can see prey from far away.
hope this helps :)
They both have different eye structures that are due to natural selection, and they both get adapted with the best shape of eyes that help them survive: the European moles have small eyes due to their underground nature, while the Sumatran tigers have large eyes.
What is the significance of the different eye shapes?Different animals have different eyes, and it depends upon their area of living, here, the eyes of European moles are small because they live underground and have less need for vision, so they have small eyes. Sumatran tigers have large eyes because they need to see prey from a distance in order to survive, so they have better vision, but it depends on the environmental pressure.
Hence, they both have different eye structures that are due to natural selection, and they both get adapted with the best shape of eyes that help them survive: the European moles have small eyes due to their underground nature, while the Sumatran tigers have large eyes.
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What isn’t an example of Homeostasis
take someone/thing
Explanation:
it means you take someone or take a thing that you can touch to a different country
The pharmaceutical industry is always pursuing new treatments for cancers. The development of new cancer drugs and therapies can help treat people who have been diagnosed with cancer and increase their survival. Which of these describes the types of cells that cancer drugs would target? Select ALL that apply.
These describes the types of cells that cancer drugs would target:
Cancer cellsStem cellsAngiogenic cellsImmune cellsWhat are stem cells?Stem cells are undifferentiated cells that have the ability to develop into many different types of specialized cells in the body. They have the potential to become cells of the various tissues and organs of the body, such as muscle, bone, cartilage, blood, and nerves, among others.
Cancer drugs can target various types of cells involved in the development, growth, and spread of cancer. The following are some of the types of cells that cancer drugs may target:
Cancer cells: Cancer drugs are designed to specifically target cancer cells and stop their growth and spread.
Stem cells: Cancer stem cells are a type of cell that can regenerate and differentiate into different types of cancer cells, making them a potential target for cancer drugs.
Angiogenic cells: These cells are involved in the formation of new blood vessels, which are necessary for the growth and spread of tumors. Cancer drugs may target angiogenic cells to prevent the formation of new blood vessels and thereby stop the growth of tumors.
Immune cells: The immune system plays a critical role in fighting cancer, and some cancer drugs may target immune cells to help boost the body's natural defenses against cancer.
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Answer:
A ,B and E
Explanation:
I am learning about this currently and taking the test.
Which is a function of a protein macromolecule?
Answer:
A. Moves things in and out of cells
In humans, r codes for right-handedness and is dominant to r, which codes for left-handedness. Kulbir is right handed, and daljit is left handed. They have three children: two right-handed and one left-handed. What is kulbir's genotype? [ select ] if kulbir and daljit have another child, what is the probability that their fourth child will be left-handed?
Kulbir's genotype is Rr and the probability of their fourth child being left-handed would be 50%.
Since Kulbir is right-handed, and right-handedness (r) is dominant to left-handedness (r), it means that Kulbir must have at least one dominant allele for right-handedness (R). Since the genotype for right-handedness can be either RR or Rr, we cannot determine the exact genotype of Kulbir without further information. However, we can conclude that Kulbir must have at least one dominant allele (R) for right-handedness.
If Kulbir and Daljit have another child, the probability that their fourth child will be left-handed (rr) depends on the genotypes of both parents. Since Daljit is left-handed (rr), we know that Daljit's genotype is rr. If Kulbir's genotype is Rr, then there is a 50% chance that Kulbir will pass on the recessive allele (r) to the fourth child. Therefore, the probability of their fourth child being left-handed would be 50%.
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Which came first the Ordovician period or the oligocene epoch
Answer: i want to say ordovician period
Explanation:
Answer:
Ordovician period
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True or False: A recessive trait masks other traits and is represented with a capital letter.
WILL MARK BRAINLYEST.
26.
What about the structure of a fat molecule makes it useful for a cell and why?
Fats serve as enzymes in the process of digestion.
The large number of carbon-hydrogen bonds allow for the storage of energy.
The fatty acid part of fats help digest food in cellular respiration.
The glycerol portion of the fat molecule is used to release energy
Is the answer three
Because they help the body absorb vitamins a, d, e, and k.
Imagine the scenario. All of the rocks used for shelter by certain reptiles are removed from a desert ecosystem. How will the removal of the rocks affect the reptiles?
Answer: The reptiles population will decrease
Explanation:
On the removal or rocks from desert ecosystem, the reptiles will not be able to survive and can become extinct.
What is desert ecosystem?Deserts are desolate areas of land with extremely high or low temperatures, little or no rainfall, and little or no vegetative cover.
Deserts are illustrations of terrestrial ecosystems that can be discovered all over the world. Not all deserts are plain, nor do they all have cacti or oases.
One of the most crucial biomes is the desert. Our planet has 15 different types of mineral deposits, 13 of which are found in deserts.
As a result, the desert is vital for mineral resources as well as the local and global economies.
As it is mentioned that the rocks are used for shelter by reptiles, they cannot survive if these shelters are taken away from them. In this case it is possibility that they can go extinct.
Thus, this is the effect that occurs due to removal of the rocks from desert.
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Help....I will mark as brainless if answered correctly
Although the birds of the Galapagos Islands looked very different from one another structurally, they all shared
something in common. What was the common thread?
A. They were all carnivores.
B. They were all nocturnal.
C. They were all different variations of the finch.
Answer:
I believe the answer is C. They were all different variations of the finch.
Explanation:
Although the birds of the Galapagos Islands looked very different from one another structurally, they all shared something in common. What was the common thread? They were all different variations of the finch.
Answer: C. They were all different variations of the finch.
Explanation:
Give one example of how weathering by wind could occur in nature.
Answer:
Wind and water cause small pieces of rock to break off at the side of a mountain. ... Example of erosion: Wind carries small pieces of rock away from the side of a mountain.
What are cell cycle regulators
Answer: A conserved set of cyclin-dependent protein kinases (Cdks) initiate or regulate events through phosphorylation of intracellular proteins, thus controlling cell cycle progression, terminal differentiation, and apoptosis.
Explanation: Your welcome! ;D
an intravenous cholangiography will help diagnose ________.
An intravenous cholangiography (IVC) is a medical imaging procedure that can help diagnose problems in the bile ducts.
During an IVC, a contrast dye is injected into a vein in the arm, which then travels through the bloodstream to the liver and bile ducts. X-ray images are then taken to visualize the flow of the dye and identify any blockages or abnormalities in the bile ducts.
IVC is commonly used to diagnose conditions such as gallstones, tumors, and strictures (narrowing) in the bile ducts. It can also help detect other abnormalities, such as inflammation or infection in the liver or bile ducts.
Overall, IVC is a useful tool for evaluating the biliary system and can provide important information for the diagnosis and treatment of various liver and gallbladder conditions.
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Experiments conducted by Louis Pasteur disproved the concept of
spontaneous generation. What does spontaneous generation mean?
• A. Nonliving things can produce living things.
• B. New cells come from preexisting ones.
• c. Living things can mutate into new species.
• D. Living things can pass their traits to their offspring.
Nonliving things can produce living things is the concept of
spontaneous generation
By spontaneous generation, what do you mean?
The ancient idea that used spontaneous generation to explain the genesis of life, which is the hypothetical mechanism by which live entities grow from nonliving matter.
According to the theory of spontaneous generation, life spontaneously developed from dead, decaying, and rotting substances like straw and muck. Louis Pasteur refuted this hypothesis. Louis Pasteur provided evidence that pre-existing life is the source of new life.
Maggots form from rotting meat, fleas appear from dust, and mice appear from bread or wheat left in a dark place are common examples of spontaneous generation.
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Which of the following is considered the gold standard in evaluating cardiac function and volume status? A: Thermodilution pulmonary artery catheter B: Esophageal doppler monitoring C: Pulse contour analysis D: Arterial blood pressure
The gold standard in evaluating cardiac function and volume status is thermodilution pulmonary artery catheter (PAC). The Correct option is A
This technique involves the insertion of a catheter into the pulmonary artery through a peripheral vein, and a small amount of saline is injected into the bloodstream. The resulting change in temperature is detected by a thermistor on the catheter tip and used to calculate cardiac output and other hemodynamic parameters.
PAC can provide direct measurements of central venous pressure, pulmonary artery pressure, and cardiac output, making it an essential tool in managing critically ill patients. However, it is an invasive procedure and requires expertise to interpret the data accurately.
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Identify the correct statement about conservation biology. 1.The natural genetic diversity of species varies from species to species. 2.When a species rebounds from near extinction to its original population numbers, genetic diversity also rebounds. 3.Edge effects influence all species negatively.
The correct statement about conservation biology is that the natural genetic diversity of species varies from species to species.
This means that different species have different levels of genetic diversity within their populations, which is an important consideration in conservation efforts.
Conservation biology is a field that focuses on understanding and protecting biodiversity and the natural environment. It encompasses various aspects of conservation, including the preservation of species, ecosystems, and genetic diversity.
The first statement, "The natural genetic diversity of species varies from species to species," is correct. Genetic diversity refers to the variation in genetic characteristics within a species' population. Different species have different levels of genetic diversity. Some species naturally have higher genetic diversity, which can provide them with a greater ability to adapt to changing environments, resist diseases, and maintain healthy populations. In contrast, other species may have lower genetic diversity, which can make them more susceptible to threats such as inbreeding depression or environmental changes.
The second statement, "When a species rebounds from near extinction to its original population numbers, genetic diversity also rebounds," is not necessarily true. When a species undergoes a severe population bottleneck or experiences a drastic reduction in numbers, it can lead to a loss of genetic diversity. Even if the species rebounds in terms of population size, the genetic diversity may not fully recover. It takes time and specific conservation strategies, such as genetic rescue or translocation, to restore genetic diversity in a recovered population.
The third statement, "Edge effects influence all species negatively," is incorrect. Edge effects refer to the changes in environmental conditions and species interactions that occur at the edges of habitats, such as where a forest meets a cleared area. While edge effects can have negative impacts on some species, such as increased vulnerability to predators or altered microclimates, they can also create new habitats and ecological niches that benefit other species. The impact of edge effects varies depending on the specific species and ecological context.
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three ways that CRISPR is making genetic engineering more accessible
Answer:
Precision and accuracy: CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology allows for precise and accurate editing of specific genes within a genome. This technology is much more efficient and effective than previous methods of genetic engineering, such as zinc-finger nucleases and TALENs, which were much more difficult and expensive to use.
Cost and accessibility: The cost of CRISPR technology has dropped dramatically since its discovery, making it more accessible to researchers and scientists. This has led to a proliferation of research in the field of genetic engineering, with more and more labs and institutions adopting CRISPR technology.
Flexibility: CRISPR technology can be used in a wide range of organisms, including bacteria, plants, animals, and even humans. This versatility has made it possible to study and edit genes in a variety of organisms, leading to new insights and discoveries in the field of genetics.
Explanation:
Hello this is for the hardy Weinberg problems , I need help with the conclusion questions
A population is in Hardy-Weinberg equilibrium if the genotype frequencies of the population are equal to the expected frequencies of the next generation, that is, if:
\(\begin{gathered} P=p^2 \\ H=2pq \\ Q=q^2 \end{gathered}\)The frequencies of the population are:
P= f(SS)= 0.9025
H= f(Ss)= 0.095
Q= f(ss)= 0.0025
The population of frogs has 8000 individuals, 20 of which are homozygous recessive for the trait "being spotted"
Assuming Hardy-Weinberg equilibrium you can calculate the frequency of the recessive allele as follows:
The genotypic frequency of the homozygous recessive is
\(Q=q^2=\frac{20}{8000}\)Apply the square root to determine the value of q:
\(\begin{gathered} q=\sqrt[]{\frac{20}{8000}} \\ q=\frac{1}{20} \\ q=0.05 \end{gathered}\)The allelic frequencies are complementary, which means that they add up to 1, knowing the value of q you can calculate the frequency of the dominant allele p:
\(\begin{gathered} p+q=1 \\ p=1-q \\ p=1-0.05 \\ p=0.95 \end{gathered}\)Predict the genotype frequencies of the offspring on equilibrium:
Homozygous dominant SS
\(\begin{gathered} P=p^2 \\ P=0.95^2 \\ P=0.9025 \end{gathered}\)Heterozygous Ss
\(\begin{gathered} H=2pq \\ H=2\cdot0.95\cdot0.05 \\ H=0.095 \end{gathered}\)Homozygous recessive:
\(\begin{gathered} Q=q^2 \\ Q=0.05^2 \\ Q=0.0025 \end{gathered}\)Compare the results:
As you can see the genotype frequencies of the current population are equal to the genotype frequencies of the original population, you can say that the population is in Hardy-Weinberg equilibrium.
Once the population reaches equilibrium it does not change, i.e. the frequencies are the same from one generation to the other, unless some outer factors, like deforestation, create a drastic change in the genetic pool (for example, by eliminating/ adding individuals or isolating small portions of the population)
On the other hand, if the population is evolving, i.e. the genotypic frequencies are changing, and the observed genotype and allele frequencies will change from one generation to the next one.
If you concluded that the population is in equilibrium, then it is not possible for it to be evolving as the frequencies do not change for a population in equilibrium as they do when the population is evolving.
This means that the population is not evolving.
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Describe two problems a plant might encounter during reproduction
Answer:
During reproduction plant might experience absence of pollinators or presence of low temperature
Explanation:
Following can be the problems a plant might encounter during reproduction
Presence of Low temperature for long time: Due to presence of low temperature during the reproduction of plants for long period of time it will break its dormancy and freeze the blossom or developing fruitAbsence of pollinators: As e know pollinators play a vital role in reproduction. In the absence of Pollinators (i.e., beans) plants are not able to exchange the nectar carryingPlant reproduction takes place through the asexual and sexual process called pollination. They can either self-pollinate or cross-pollinate.
Reproduction needs the fusing of both the male and female gametes and fuse to male the seed that bear the fruit. During reproduction, the plants may face a lack of pollen grains and the presence of low temperature.Learn more about the two problems a plant might encounter during reproduction.
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What is the base pairing rule state