what is true of binding pockets?

Answers

Answer 1

Binding pockets, also known as binding sites, are specific regions on the surface of a molecule, usually a protein, where other molecules can bind. They play a crucial role in various biological processes and molecular recognition events.

Here are some important characteristics of binding pockets:

1. Specificity: Binding pockets are highly specific, meaning they can only bind to certain molecules, called ligands. This specificity is due to the unique shape, size, and chemical properties of the pocket, which allows it to recognize and bind to its target ligand.


2. Complementary structure: The structure of a binding pocket is complementary to the structure of its ligand. This means that the shape, size, and chemical properties of the pocket match those of the ligand, allowing for a tight and stable interaction between the two.


3. Non-covalent interactions: Binding between the pocket and its ligand typically involves non-covalent interactions, such as hydrogen bonding, electrostatic interactions, van der Waals forces, and hydrophobic interactions. These weak interactions allow for reversible binding and facilitate the dynamic nature of molecular recognition events.


4. Regulation of biological processes: Binding pockets play a key role in regulating various biological processes, such as enzyme catalysis, signal transduction, and protein-protein interactions. When a ligand binds to a binding pocket, it can either activate or inhibit the function of the protein, thereby modulating the associated biological process.


5. Drug targets: Many drugs work by binding to specific binding pockets on target proteins, thereby modulating their activity. Understanding the structure and function of binding pockets is therefore critical for the design of new drugs and therapies.


In summary, binding pockets are specific regions on the surface of a molecule that allow for the recognition and binding of ligands. They exhibit specificity, complementary structure, and non-covalent interactions, which are important for regulating biological processes and serving as drug targets.

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Related Questions

what are stem cells and how may they be used

Answers

Answer:

cells from which all other cells with specialized functions are generated.

Explanation:

they may be used by dividing into two or more cells called the daughter cells

Stem cells are cells with the potential to develop into many different types of cells in the body. They serve as a repair system for the body. There are two main types of stem cells: embryonic stem cells and adult stem cells.

5. What process happens when rocks break down due to reaction with water,
carbon dioxide, oxygen and organic acids?
A. Biological Engineering
B. Chemical Engineering
C. Electrical Engineering
D. Mechanical Engineering
If your score is
sted by the ever
4- 5 Very good! You may still read the module but you are already
knowledgeable with the topics that we are to discuss.
2-3 Good! Go over the items that you find difficult and then you may proceed
to the lessons in this module that you don't understand. .
to​

Answers

Answer:

Chemical engineering

Explanation: I am not really that good at science but my opinion is that it is chemical engineering because the process of the rock breaking down with the listed factors of water, carbon dioxide etc. If you are not sure you can also look of the definition for each of the engineering factors...

Chickens are divided into two groups: broilers and layers. What is one point of comparison between these two types of chickens?

A.
There are more males than females.

B.
There are equal numbers of layers and broilers.

C.
There are more layers than broilers.

D.
There are more broilers than layers.

Answers

There are more broilers than layers. Chickens are divided into two main groups: broilers and layers. Broilers are chickens that are raised for their meat, while layers are chickens that are raised for their eggs. One point of comparison between these two types of chickens is the number of broilers and layers. In general, there are more broilers than layers because broilers are raised in much larger numbers than layers. This is because the demand for chicken meat is much higher than the demand for eggs, so more chickens are raised for meat than for eggs. Therefore, the answer to the question is that there are more broilers than layers.

I NEED HELP ASAP I'LL MARK BRAINEIST
Why is the convection zone called “convection”?
use clues and complete sentences

Answers

Answer:

They look very much like the cells you can see at the surface of a pot of boiling water. We call them convection cells because they are due to convection, the physical mechanisms responsible for the boiling water.

Explanation:

mark as brainiest

Answer:

Physics. the transfer of heat by the circulation or movement of the heated parts of a liquid or gas.

Meteorology. the vertical transport of atmospheric properties, especially upward (distinguished from advection).

the act of conveying or transmitting.

3.
How does mass extinction affect species that survive?
There are no surviving species if a mass extinction occurs.
They fill new roles in the changed environment.
They will soon become extinct.
They combine gene pools.

Answers

Answer:

They fill new roles in changed environment

Explanation:

I don’t know what to do anymore please help ‼️

I dont know what to do anymore please help

Answers

Answer:

I think it's " C and D" not to sure about "C" but one of the answers is definitely " D"

Explanation:

identify at least two ways photoperiodism and phototropism are similar. what makes them different

Answers

Photoperiodism and phototropism are both responses of plants to light, and they share some similarities in terms of their effects on plant growth and development. One of the similarities is that both processes involve plant receptors that sense light, and they trigger specific physiological responses in plants.

Another similarity is that both photoperiodism and phototropism are influenced by the intensity and duration of light exposure. For example, in photoperiodism, the length of exposure to light determines the plant's developmental stage, while in phototropism, the direction and intensity of light influence the plant's growth towards or away from the light source.
However, there are also some differences between photoperiodism and phototropism. The main difference is that photoperiodism is a response to the duration of light exposure, while phototropism is a response to the direction of light. Photoperiodism controls the timing of key developmental stages, such as flowering, while phototropism controls the orientation of plant growth.
Additionally, photoperiodism is more sensitive to changes in day length, while phototropism is more influenced by the direction and intensity of light. Finally, photoperiodism is a universal response in plants, while phototropism is observed only in certain plant species.

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TRUE/FALSE. the host defenses include immunity which is present at birth, and immunity which is acquired over time and specific in its action.

Answers

The statement "host defenses include immunity that is present at birth, and immunity that is acquired over time and specific in its action" is true, because Innate immunity is present since birth and is the first line of defense against pathogens.

The immune system's overall function is to identify and destroy antigens such as bacteria and viruses. It consists of physical barriers such as the skin, chemical barriers such as enzymes in sweat, and biological barriers such as immune cells and antibodies. The immune system is the body's host defense against pathogens and other harmful substances that can cause disease.

Immunity refers to the body's ability to resist infection or harmful substances by producing antibodies or sensitized white blood cells. In the immune system, there are two primary types of immunity: innate and adaptive immunity.

Innate immunity: This type of immunity is present from birth and is the first line of defense against invading pathogens. Skin and mucous membranes, as well as certain white blood cells known as phagocytes, are examples of innate immunity.Adaptive immunity: This type of immunity is acquired over time and is specific to a particular pathogen. The adaptive immune system includes white blood cells known as lymphocytes, which generate antibodies and recognize specific antigens on pathogens.

Hence, the given statement is true.

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What change to the following molecule's structure would result in a saturated fat?

What change to the following molecule's structure would result in a saturated fat?

Answers

Answer:

It needs to gain a Hydrogen atom to eliminate the double bond between the two carbons.  

Explanation:

Unsaturated fat has one or more double bonds in its molecule. Saturated fat has a single bond. If you want an unsaturated fat to become saturated it needs to gain more more hydrogen atoms which will eliminate the double bonds between carbons of the unsaturated fat.

Hope this helped :)  


Write an essay about a
specific organism that is
endangered or threatened
and the reason for its
declining population.
Include any efforts made to
protect and conserve this
organism. At least 200 words

Answers

The answer is An endangered species is a type of organism that is threatened with extinction. Species are becoming endangered for two main reasons: habitat loss  and loss of genetic variation.

Habitat loss can occur naturally. The dinosaurs, for example, lost their habitat about 65 million years ago. The hot, dry Cretaceous climate  changed very quickly, most likely due to an asteroid impact on Earth. The asteroid's impact threw debris high into the atmosphere and reduced the amount of heat and light reaching Earth's surface. The dinosaurs could not adapt to this new, cooler habitat. The dinosaurs were threatened with extinction and then died out.

Human activities can also contribute to habitat loss. The development of settlements, industry and agriculture reduces the habitat of native organisms. This can be done in a number of  ways.

Development may directly remove native habitats and species. In the Amazon rainforest in South America, developers have cleared hundreds of thousands of hectares. Clearing a piece of land means removing all trees and vegetation. The Amazon rainforest is being cleared for ranching, logging and urban use. That means the habitat can support fewer cougars. However, since large parts of the Sierra Nevada, Rocky and Cascade mountain ranges remain undeveloped, cougars are not in danger.

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Ferns, such as the one in the picture, can be found today. They are usually found
growing in warmer climates. However, fossils of ferns have been found in places with
cold climates where it often snows today. What can we conclude about the places
where the fossils of ferns have been found?

A. Ferns used to live in cold climates.

B. These places once had a warmer climate.

C. Someone tried to grow ferns in cold climates.

D. These places once had a colder climate.

Ferns, such as the one in the picture, can be found today. They are usually foundgrowing in warmer climates.

Answers

Answer:

B. These places once had a warmer climate.

Explanation:

They're fossils meaning they're extremely old therefore the climate they once grew in was suitable for its needs until the climate changed causing them to die.

What are the 4 parts of naturalization test?

Answers

Answer: The English test has three components: reading, writing, and speaking.

Explanation:

Prophage refers to: (please give right answer only)​

Answers

Answer:

: an intracellular form of a bacteriophage in which it is harmless to the host, is usually integrated into the hereditary material of the host, and reproduces when the host does.

Will give brainliest if you give the correct answer!
What similarities and differences do you see between the organisms in image 1?

Will give brainliest if you give the correct answer! What similarities and differences do you see between

Answers

Answer:

The similarities I see is that all organisms are standing on two feet, they have the same stance, and all have two feet and two arms.

The difference I see is the shape of the skull and the height.

Explanation:

I hope I have helped

what is measurement

Answers

Measurement is defined as the act of measuring or the size of something. An example of measurement means the use of a ruler to determine the length of a piece of paper. An example of measurement is 15" by 25".

Answer:

This is the act of measuring something or the act of taking the length, weight or height of something,e.t.c.

Explanation:

When describing a group of animals, you speak about an ancestral species and some but not all of its descendants. This is an example of a _____. Group of answer choices monophyletic group polyphyletic group paraphyletic group

Answers

Answer:

This is an example of a paraphyletic group.

Explanation:

Paraphyletic groups is a group that contains only part of the descendants of a common ancestor. A group is constituted as paraphyletic when one or more holophyletic groups are subtracted from a clade (evolutionary branch). Traditional classifications are loaded with paraphyletic groups, such as invertebrates, pteridophytes, opposites. In each of these cases the group is defined by the exclusion of a smaller group within a larger one. An example is the reptiles are a paraphyletic group, since when we refer to them we are excluding mammals and birds even though they are taxa that evolutionarily descend from reptiles.

hat happens when humans burn fossil fuels? Carbon is released into the atmosphere. Carbon is removed from the atmosphere. Carbon is added to the the carbon cycle. Carbon is destroyed.

Answers

Answer:

Carbon is released into the atmosphere.

Explanation:

Carbon is released into the atmosphere. So, the correct option is (A).

What is Carbon?

Carbon is defined as a chemical element, like hydrogen, oxygen, lead or any other element that is very abundant in the periodic table. It exists in pure or nearly pure forms such as diamond and graphite, but can also combine with other elements to form molecules.

Carbon is used in metal smelting in the form of charcoal (from wood) and coke (from coal) as impure carbon, which is particularly important in the iron and steel industries. Graphite is used in pencils, to make brushes in electric motors, and in furnace linings, while activated charcoal is used for purification and filtration.

When we burn we the human fossils, some gases like Carbon is released into the atmosphere.

Thus, Carbon is released into the atmosphere. So, the correct option is (A).

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(04.01 LC)
Which of the following conditions is necessary for natural selection to occur? (3 points)
More organisms are born than can survive.
Each individual organism that is born must survive.
There must be no mutations among organisms.
There must be no variation among organisms.

Answers

Answer:

A

Explanation:

The condition that is necessary for the natural selection to occur is that each individual organism that is born must survive. The correct option is B.

What is natural selection?

Natural selection is the process by which living organism populations adapt and change.

Individuals in a population are naturally variable, which means they differ in some ways. This variation indicates that some people have traits that are better suited to their environment than others.

Natural selection, Darwin proposed, is a mechanism for evolution in which heritable traits that help organisms survive and reproduce become more common in a population over time.

The phrase "survival of the fittest" refers to the process of natural selection, a mechanism that drives evolutionary change.

The condition for natural selection to occur is that each individual organism that is born must survive.

Thus, the correct option is B.

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Infection by the human immunodeficiency virus (HIV) into a target cell is shown here. Which statements are supported by the model of HIV infection? Select ALL that apply.

Answers

Answer:

The HIV genome is originally a RNA based genome.

Explanation:

Human immunodeficiency viruses are the one which infects human over time. The virus infects human body cells and progresses towards immune system failure which creates life threat for a patient. The disease is incurable till date but the effects can be slowed down by the medication and treatments. The disease in contagious and spreads by transfer of infected blood.

Answer:

B) The HIV genome is originally a RNA-based genome.

C) The HIV genome is incorporated into the host's genome.

E) Proteins on the cell surface recognize proteins on the viral surface during

attachment.

Explanation:

What are the fundamental methods, models, or theories in
nanotribology? Please be as explicative as you can.

Answers

The fundamental methods, models, and theories in nanotribology include Atomic Force Microscopy (AFM), Molecular Dynamics (MD) simulations, Contact Mechanics, Surface Chemistry, and Lubrication Theory.

Nanotribology, also known as nanoscale tribology, is the study of friction, wear, and lubrication at the nanoscale level. It focuses on understanding the fundamental mechanisms and behaviors of surfaces and interfaces when subjected to relative motion on the nanometer scale.

There are several fundamental methods, models, and theories employed in nanotribology research:

Atomic Force Microscopy (AFM): AFM is a widely used technique that allows for the measurement and manipulation of surfaces at the atomic and molecular scale. It provides detailed information about surface topography, friction, and adhesion forces.

Molecular Dynamics (MD) Simulations: MD simulations use numerical methods to simulate the motion and interactions of atoms and molecules. These simulations provide insights into the behavior of surfaces, lubricants, and additives at the nanoscale, allowing for the prediction of friction and wear properties.

Contact Mechanics: Contact mechanics is the study of the deformation and interaction between contacting surfaces. It involves the analysis of forces, stresses, and deformation at the interface, which helps in understanding the origins of friction and wear.

Surface Chemistry: Surface chemistry plays a crucial role in nanotribology. It involves studying the chemical composition, structure, and reactivity of surfaces, as well as the formation of boundary layers and tribofilms during sliding.

Lubrication Theory: Lubrication theory focuses on understanding how lubricants reduce friction and wear between surfaces. It includes concepts such as boundary lubrication, hydrodynamic lubrication, and elasto hydrodynamic lubrication, which describe different mechanisms of lubrication at the nanoscale.

These methods, models, and theories collectively contribute to advancing our understanding of nanotribology and have applications in various fields, including materials science, nanotechnology, and engineering.

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Up to this point, did you notice any differences between the development of male and
female gametes?
Explain​

Answers

Both require different hormones that start the production of gametes for example oestrogen is produced in women and testosterone is produced in males

Both male and female gametes are produced by different organs and in different sizes.

The main difference between male and female gametes is that male gametes which are known as sperm cells are produced in large numbers by the male reproductive organs whereas female gametes are called egg cells which are produced single at a time by the female reproductive organs.

Both male and female gametes are formed by meiosis type cell division. The female gamete is a large in size and motile while the male gamete is small in size and also motile so we can conclude that both gametes are produced by different organs, numbers and sizes.

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Is there equity in the worlds energy consumption?

Answers

Answer:

Yes.

Explanation:

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stress provokes the what to initiate a memory trace that boosts activity in the brain's memory-forming areas?

Answers

Stress provokes the amygdala to initiate a memory trace that boosts activity in the brain's memory-forming areas.

The amygdala is a small almond-shaped structure located in the brain's temporal lobe that plays a key role in the processing of emotions, particularly negative emotions like fear and anxiety. The amygdala also plays an important role in memory formation, particularly the formation of emotionally charged memories.

Stress is a type of emotion that activates the amygdala and triggers the release of stress hormones like cortisol, which in turn boosts activity in the brain's memory-forming areas. This is why stress can sometimes improve memory performance, but too much stress can also have the opposite effect and impair memory function.

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during the set-up of the respirometer you forget to soak one of the cotton pieces in koh. how would you expect this to affect the migration of the methylene blue dye as the worms respire?

Answers

If one cotton piece is not soaked in KOH during the setup of the respirometer, the migration of the methylene blue dye would be affected as the worms respire due to the increased concentration of carbon dioxide inhibiting its movement.

If you forget to soak one of the cotton pieces in KOH during the setup of the respirometer, it would affect the migration of the methylene blue dye as the worms respire. The cotton soaked in KOH is used to absorb carbon dioxide produced during respiration, preventing it from interfering with the movement of the dye.

Without the cotton soaked in KOH, the carbon dioxide produced by the worms would not be effectively removed from the respirometer. This would result in a higher concentration of carbon dioxide inside the respirometer compared to the control setup where all cotton pieces were soaked in KOH.

As a result, the presence of carbon dioxide would inhibit the movement of the methylene blue dye. Carbon dioxide is known to affect the pH of the surrounding medium, which can lead to a change in the color of the dye.

In conclusion, if one cotton piece is not soaked in KOH during the setup of the respirometer, the migration of the methylene blue dye would be affected as the worms respire due to the increased concentration of carbon dioxide inhibiting its movement.

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major histocompatibility complex (mhc) molecules, with human leukocyte antigens (hlas), are markers on all nucleated cells and have an important role in:

Answers

The major histocompatibility complex (MHC) molecules, with human leukocyte antigens (HLAs), are markers on all nucleated cells and have an important role in the immune system.

MHC molecules are responsible for presenting antigens to T cells, which are a type of lymphocyte that plays a vital role in the immune system. Antigens are molecules that are recognized by the immune system, and they can be derived from pathogens, cancer cells, or other foreign substances. When an antigen is presented to a T cell by an MHC molecule, it can trigger an immune response.

There are two types of MHC molecules: MHC class I and MHC class II. MHC class I molecules are found on all nucleated cells, and they present antigens to cytotoxic T cells. Cytotoxic T cells are responsible for killing cells that have been infected with viruses, as well as cancer cells. MHC class II molecules are found on antigen-presenting cells, such as dendritic cells, macrophages, and B cells. They present antigens to helper T cells, which are responsible for activating other cells of the immune system.

Therefore, the major histocompatibility complex (MHC) molecules, with human leukocyte antigens (HLAs), are markers on all nucleated cells and have an important role in the immune system by presenting antigens to T cells, which can trigger an immune response. There are two types of MHC molecules: MHC class I and MHC class II, which present antigens to cytotoxic T cells and helper T cells, respectively.

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The complete question is-

What is the role of the major histocompatibility complex (MHC) molecules, with human leukocyte antigens (HLAs), in the immune system?

What is the definition of gully ?

Answers

Answer:a ravine formed by the action of water.

Explanation:

It’s kind of like a rain ditch on the road

A ravine formed by the action of water.

Can someone figure this out for me? I've been stuck on this for hours

Can someone figure this out for me? I've been stuck on this for hours

Answers

1. Sugar
2. Phosphate
3. Nitrogenous base

Arrange these energy sources from highest to lowest percentage of worldwide use. 1, Nuclear 1. Coal * Hydroelectric​

Answers

Explanation:

hydro coal nuclear i think it would like thst

The arrangement of the energy according to the highest to the lowest percentage of worldwide use is coal, hydroelectric and nuclear. The arrangement is 2, 3, and 1.

What is energy?

Energy is a quantitative property that is used in doing any work. The energy is always transferred from one form to another form. It is present in the conserved form.

The energy which is used majorly is coal, then hydroelectricity, which is made by water then the nuclear power plant.

Thus, the arrangement is 2. Coal, 3, hydroelectric, 1. Nuclear energy.

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Which event is caused by the transmission of waves?
OA. A sound echoes through a canyon.
OB. A fish in a pond looks larger than it is.
OC. A sound is heard through a door.
D. An image of a face appears in a mirror.

Answers

The correct answer is OC (sound through a door)


How do I know this?

There are four things a wave can do.

1) reflection - this is when a wave hits something and bounces back perfectly.

2) absorption - this is when a wave gets absorbed (it does not come out the other side).

3) transmission - this is what your question is talking about. This is when a wave passes through something and comes out the other side unchanged

4) refraction- this is when a wave passes through something and gets bent

When we hear an echo, this is because a sound wave has been reflected.

When a fish looks larger than it really is, this is because the light wave that allows us to see this fish is bending


When you see yourself in the mirror, this is because light waves are reflected.

Sound is heard through a door, because the sound wave is *transmitted* through the door and comes out the other side. That’s why we can hear it.

Hope that makes sense

Can someone plz give me the answer I need 2 more after and I need these to pass

Can someone plz give me the answer I need 2 more after and I need these to pass

Answers

Answer:

Wait a second i will help let me get somthing

Explanation:

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What is the purpose of this excerpt from the article "What Is GIS?"?GIS also can be used for complex modeling to answer a wide range of "what if" and ecosystem simulation questions. These may be cartographic models designed to document the co-occurrence or interrelationship of multiple data layers or they may be hypothetical research models designed to mimic natural ecological systems. Similarly, modeling with GIS can be used to predict the impacts that one set of parameters will have on another. For example, wetlands, soils, hydrography, climatology and elevation data can be combined to model flooding within a river system. Upstream changes in land use within the same system can be modeled to determine the potential impact of conversion of a forested floodplain to residential development or to agriculture. As a result, both natural system responses to storm events and the impact of human land use decisions can be assessed prior to the proposed action. Assume the short-run average total cost for a perfectly competitive industry decreases as the output of the industry expands. In the long run, the industry supply curve will: a. have a positive slope. b. have a negative slope. c. be perfectly horizontal. d. be perfectly vertical. Describe the levels of organizationamongst living things Which manifestations are related to target organ disease from hypertension? A stone is thrown in a verticallyupward direction with a velocityof 5 ms. If the acceleration of thestone during its motion is 10 ms?in the downward direction, whatwill be the height attained by thestone and how much time will ittake to reach there? Reverend Hale arrives at the Proctor's house to inquire about their religious standingsince Elizabeth has been mentioned in court. He asks John about his spiritual lifethen asks him to recite the 10 commandments as a sign of upstanding character.John Proctor can't bring himself to recite which commandment? An eagle flying in the air over water drops an oyster from a height of 39 meters. The distance the oyster is from the ground as it falls can be represented by the function h(t) = -4.9t^2+ 39, where t is time measured in seconds. To catch the oyster as it falls, the eagle flies along a path represented by the function g(t) = -4t + 27. Part A: If the eagle catches the oyster, then at what height does the eagle catch the oyster Part B: After how many seconds does it take the eagle to catch the oyster Simplify the expression 6C5.a.6.b. 24C. 30d. 720 The peripheral nervous system transfers information from the _______ to the rest of the body.a. interneuronsb. sensory neuronsc. braind. glands 1. Match the following Court with the correct association taken in Supreme Court Decisions:1. The Rehnquist Court2. The Warren Courta. Associated with judicial activism because of its far-reaching decisions that were not always directly connected to the immediate case.b. 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