In a transamination process with alpha-ketoglutarate, the amino acid leucine produces the following product.
With an example, define transamination reaction.The most typical reaction type that is catalysed by PLP-dependent enzymes is transamination. Living cells reversibly convert the amino group from an amine (like -aminobutyrate) or alpha-amino acid (like aspartate) to a alpha-keto carboxylic acid (like alpha-ketoglutarate).This is a crucial biological activity.Where do reactions of transamination take place?A number of tissues, including the kidney, small intestine, muscles, and adipose tissue, participate in the metabolism of amino acids, although the liver is the primary location.
What resulted from the transamination reaction?The availability of -keto acids affects the outcome of transamination processes. The end products are often either alanine, aspartate, or glutamate since the metabolism of fuels produces the matching alpha-keto acids.learn more about transamination process here
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mesissner corpuscle anterior spinothalmic tract?
Meissner's corpuscles and the anterior spinothalamic tract are both important components of the somatosensory system in the human body.
Meissner's corpuscles are specialized sensory receptors located in the skin, particularly in the fingertips, palms, and soles of the feet. These receptors are responsible for detecting light touch, pressure, and low-frequency vibrations. When the skin is stimulated, the Meissner's corpuscles send signals to the brain through the peripheral nervous system and spinal cord, allowing us to perceive sensations such as texture, shape, and movement.
The anterior spinothalamic tract is a neural pathway that carries sensory information related to crude touch, pressure, and temperature from the skin to the brain. The tract runs along the anterior (front) part of the spinal cord and eventually synapses in the thalamus, a structure in the brain that plays a critical role in sensory processing. Once the information reaches the thalamus, it is further processed and directed to the appropriate areas of the cerebral cortex, where it is interpreted and integrated with other sensory information.
Overall, Meissner's corpuscles and the anterior spinothalamic tract work together to allow us to perceive and respond to various tactile sensations. While they are just two small components of the larger somatosensory system, they play crucial roles in our ability to interact with the world around us.
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Which statement about AMP and energy is true? 1. AMP releases energy as it makes ATP 2.AMP absorbs energy when it breaks bonds 3.AMP releases energy when formed 4.AMP has one phosphate molecule
Answer:
The correct answer is - 4. AMP has one phosphate molecule.
Explanation:
AMP or adenosine monophosphate is the secondary messenger and major component of ATP (the cellular energy form). As suggested by the name it has only one molecule of phosphate, unlike ADP that has two and ATP where three phosphates are attached to one sugar molecule and nucleobase adenine.
AMP has the least energy in comparison to the ADP and ATP as more energy releases when bonding breaks. It is interconverted to ADP and ATP in metabolic processes.
What are the characteristics on the side of the diagram called?Characteristics: amniotic egg, tetrapod, vertebrae, develop from blastula, common ancestor.
The diagram in the picture is a cladogram, a diagram that depicts rellationships between different groups of organisms, reconstructing evolutionary history. The cladogram is composed of nodes, clades and roots (initial ancestor, common to all).
true or false: natural selection is only one of several possible causes of evolution.
The given statement "Natural selection is only one of several possible causes of evolution" is True because natural selection is a mechanism of evolution, but it is not the only cause of evolutionary change.
Other mechanisms include genetic drift, gene flow, and mutation. Genetic drift is the random fluctuation of gene frequencies in a population due to chance events, such as a natural disaster or random mating. Gene flow is the movement of genes from one population to another, which can introduce new traits into a population.
Mutation is a change in the DNA sequence that can lead to new traits or genetic variation. While natural selection is often the most well-known mechanism of evolution, it is important to recognize that other factors can also play a significant role in shaping the genetic makeup of a population over time.
Understanding the different mechanisms of evolution is crucial to understanding how biodiversity is generated and how species change over time.
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Natural selection is indeed one cause of evolution, but there are several others including gene flow and genetic drift. Not all evolution is adaptive, and evolution is neither moving towards a preconceived ideal nor is it random. It is influenced by various processes and their impact on a population's genetic and phenotypic variance.
Explanation:The statement is true: natural selection is indeed one of several causes of evolution. Natural selection drives evolution by favoring individuals and traits that are better adapted to survival in a specific environment. However, natural selection is limited by the existing genetic variation in a population and the new alleles that arise through mutation and gene flow.
Furthermore, not all evolution is adaptive, and other forces such as genetic drift also significantly influence evolution, often introducing deleterious alleles into a population's gene pool. Biological evolution is not moving towards a preconceived ideal nor is it random; instead, it is the sum of various processes and their influence on a population's genetic and phenotypic variance.
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Bent little finger (B) is dominant over straight little finger (b). A student has bent little finger, but their Mom has straight little finger. Without even knowing the Dad's phenotype, what is the student's genotype? O a. BB Ob. Bb O c. bb O d. There is no way to be sure, because we don't know Dad's genotype. Value: 2 Widow's peak is dominant over lacking a widow's peak. Sophia has a widow's peak, just like both her parents. Are we sure she is PP? O a. Yes, she is PP because both parents have the dominant trait. O b. No, there is still a chance she could be Pp. That might occur if either parent was Pp. O c. No, she could be PP, Pp, or pp. All are possible depending on her parent's genotypes. Value: 2 Dark brown eyes (B) are dominant over light colored eyes (b). A student has blue eyes (light), but she is adopted. Do we know her genotype? O a. BB O b. bb O c. There is no way to be sure without knowing the genotype of at least one of her parents. O d. Bb
The student's genotype is either Bb or BB.
Based on the given information, we know that a bent little finger (B) is dominant over a straight little finger (b). The student has a bent little finger, indicating that they possess the dominant trait. However, since we do not know the genotype of the student's father, we cannot determine the exact genotype of the student.
If the student's mother has a straight little finger (bb), then the student must have inherited the bent little finger allele from their father. In this case, the student's genotype would be Bb, with one copy of the dominant allele and one copy of the recessive allele.
On the other hand, if the student's mother has a bent little finger (Bb or BB), the student could have inherited either a dominant allele from the mother (BB) or one copy of the dominant allele from the mother and one copy of the recessive allele from the father (Bb). Therefore, the student's genotype could be either BB or Bb.
In conclusion, without knowing the genotype of the student's father, we cannot determine the exact genotype of the student. However, based on the given information, the student's genotype is either Bb or BB.
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PLEASE HELP
Many plants have the ability to respond to herbivores. Some plants produce substances
which are distasteful or toxic in response to an herbivore attack. Which of these is the LEAST correction description of the plant system interactions involved?
A. Carbon dioxide diffuses through stoma into leaf tissues, where it is fixed into organic compounds
which may serve as building blocks for chemical defenses.
B. Root systems obtain water and key minerals from the soil where they are transported to the affected site.
C. Shoot systems carry carbon dioxide, water and nutrients from leaves directly to the affected
plant part, where chemical defense molecules are produced.
D. Chemicals found in a herbivore's saliva trigger chemical messengers which trigger production of
defense molecules
Answer:
I'm pretty sure that the answer is d :)
Explanation:
<3
Answer:
yeah
Explanation:
Mechanical Defenses
The first line of defense in plants is an intact and impenetrable barrier composed of bark and a waxy cuticle. Both protect plants against herbivores. Other adaptations against herbivores include hard shells, thorns (modified branches), and spines (modified leaves). They discourage animals by causing physical damage or by inducing rashes and allergic reactions. Some Acacia tree species have developed mutualistic relationships with ant colonies: they offer the ants shelter in their hollow thorns in exchange for the ants’ defense of the tree’s leaves.
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12. Explain how blood is a suspension.
Thank you ☺️
A cell has unsuccessfully activated an unfolded protein response to relieve the stressful situation from misfolded proteins. What is likely to follow? a. cell grows to dilute the effects of the unfolded proteins on the other protein complexes. b. cells temperature increases so that the proteins denature and retry to fold properly. c. cell divides so that atleast one daughter cell would survive and increase the survival of the organism.
d. apoptosis is triggered and the aberrant cell is removed. e. cell shrinks so that the unfolded proteins may be forcibly folded.
If a cell has unsuccessfully activated an unfolded protein response to relieve the stressful situation from misfolded proteins, the likely outcome is apoptosis, where the aberrant cell is triggered to undergo programmed cell death.
The unfolded protein response (UPR) is a cellular mechanism that is activated in response to the accumulation of misfolded proteins in the endoplasmic reticulum (ER). The UPR aims to restore protein homeostasis by increasing the production of molecular chaperones and reducing protein synthesis.
However, if the UPR fails to restore protein folding and alleviate ER stress, it can lead to a prolonged and severe cellular stress response. In such cases, the cell may undergo apoptosis, a programmed cell death process. Apoptosis serves as a protective mechanism to eliminate cells that are irreparably damaged or unable to recover from stress.
By triggering apoptosis, the cell sacrifices itself to prevent the accumulation of further misfolded proteins and to protect the overall integrity of the organism. Apoptosis is a tightly regulated process involving the activation of specific signaling pathways, DNA fragmentation, and the dismantling of cellular components.
Therefore, if the unfolded protein response is ineffective in resolving the stress caused by misfolded proteins, the likely outcome is the initiation of apoptosis to remove the aberrant cell and maintain the survival and functionality of the organism.
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If an oak tree has 6 chromosomes in its reproductive cells, then it means that it has 12 chromosomes in its ________cells.
If an oak tree has 6 chromosomes in its reproductive cells, then it means that it has 12 chromosomes in its somatic cells. This is like this because reproductive cells are generated by meiosis, which is a reductional cell division, producing four cells with half of the genetic material of the original cell and different from each other.
Which of the following descriptions best states how oceans and land absorb the sun's energy differently?
A.
Land retains absorbed heat longer than oceans do.
B.
Land absorbs the sun's energy slowly, while oceans absorb it more quickly.
C.
Land only absorbs radiation that is not harmful to humans.
D.
Land reflects more of the sun's energy, while oceans absorb it slowly and retain it longer.
The statement that describes the major differences as to how the oceans and the land absorbs the energy from the sun is that Land reflects the Sun's energy quickly, while oceans absorb it more slowly.
Earth's oceans are far more important than the land as a source of the heat energy which drives weather and climate. As they also absorb more sunlight and store more heat.
The sun warms up parts of the oceans. Warm waters rise just like warm air rises. So, as the warmer ocean waters begin to rise in a particular area, the cooler ocean waters from a different area will move in to replace the warmer ocean waters, and this creates our ocean currents.
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Can someone plz help
The answer for your question is B
The nuclei of both 3h and 3he have radii of 1. 5×10^−15m. With what velocity must the electron be ejected if it is to escape from the nucleus and not fall back?.
The velocity with which the electron must be ejected to escape from the nucleus and not fall back is 8.21067 x 10^8 m/s.
How the electron of the nucleus and with what velocity it must move to not fall back?According to the question provided, we know that 3H and 3E ( radii = 1.5 x 10^-15m) .We use the concept of escape velocity.Kinetic energy, K.E. = 1/2 mv^2 = P.E.1/4piEo x q1xq2/r = K xq1 xq2/r Equating the both we get 1/2mv^2v= sqrt ( 1/pi x Eo)(e^2/mxr)v=sqrt(1/pix8.85x10^-12)(1.602x10^-19)(9.11x10^-31x1.5x10^-15m)v=8.21067x10^8 m/s.To know more about Nuclei and velocity visit:
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organisms with spiny skin that exhibit pentaradial symmetry as adults, and have an endoskeleton made of calcium carbonate plates, make up what phylum?
Organisms with spiny skin that exhibit pentaradial symmetry as adults, and have an endoskeleton made of calcium carbonate plates, make up Echinodermata phylum.
PhylumInterlocking calcium carbonate plates and spines make up the skeletons of echinoderms. This skeleton is an endoskeleton since it is covered by the epidermis. Echinoderms have a deuterostomate pattern of development and a calcium carbonate endoskeleton. Sea stars are an example of an echinoderm belonging to the asteroidea class.Only marine species of echinodermata exist. The early larval stages of all echinoderms have bilateral symmetry, whereas adult echinoderms have pentaradial symmetry and an ossicular calcareous endoskeleton.The phylum of echinoderms, which has approximately 7,000 species, only exists in marine ecosystems and is highly diversified. The calcareous endoskeleton of echinoderms, which have pentaradial symmetry and a spectrum of hues due to pigment cells and toxin-containing cells, may also contain poisons.For more information on Echinodermata kindly visit to
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NEED HELP ASAP!!!
In temperate regions, a lot of animals are active in daylight and inactive at night. This is_[blank 1]_ because daytime temperatures are warm, and animals can rely on their_[blank 2]_ to find food.
blank 1: a survival disadvantage
blank 2: sight
blank 1: a survival advantage
blank 2: sight
blank 1: a survival advantage
blank 2: hearing
blank 1: a survival disadvantage
blank 2: hearing
Answer:
Explanation:
blank 1: a survival advantage
blank 2: sight
In temperate regions, a lot of animals are active in daylight and inactive at night because daytime temperatures are warm, and animals can rely on their sight to find food. This is a survival advantage because being active during the day allows animals to take advantage of the warm temperatures and find food more easily.
Which sentence about the circumcenter of a triangle is true?
b) the circumcenter for obtuse angle lies outside the triangle and opposite to that of largest angle.
What is circumcenter?The vertices of a triangle are evenly separated from its circumcenter. Within an acute-angled triangle the circumcenter is situated inside acute triangle. The circumcenter for obtuse angle lies outside the triangle and opposite to that of largest angle. The origin and center of the triangle's circumcircle, which encircles its three vertices, are shared by the triangle's circumcenter. It is possible to make a triangle and locate its circumcenter using a compass and straight edge. In this unique case, the midway of the hypotenuse is precisely where the circumcenter of a right triangle lies (longest side).
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complete question:
Which sentence about the circumcenter of a triangle is true?
a) the circumcenter for obtuse angle lies outside the triangle and opposite to that of smallest angle.
b) the circumcenter for obtuse angle lies outside the triangle and opposite to that of largest angle.
c) the circumcenter for acute angle lies outside the triangle and opposite to that of smallest angle.
d) the circumcenter for acute angle lies outside the triangle and opposite to that of largest angle.
How was the appearance of the disease causing bacteria (S strain) different from the harmless bacteria (R Strain)?
Answer:
S strain have a capsule (polysaccharides) that protects them from the defense mechanisms of infected animals. In in vitro culture, they form colonies with a smooth appearance. On the other hand, R Strain do not have the capsule present in the S cells and do not cause pneumonia. In in vitro culture, they form colonies with a rough appearance.
Explanation:
In 1928, the microbiologist Fred Griffith, who was researching various strains of pneumococcus, injected mice with the S strain and the R strain of the bacteria. The S strain was harmful, while the rough (R) strain was not. When, inactivated by heat, the S strain was injected, there were no sequelae and the mouse lived. Surprisingly, when combining strain R (non-lethal), with strain S inactivated by heat (non-lethal), the mouse died. In addition, Griffith found live S-strain cells. R Strain apparently became S strain. This finding could not be explained, until in 1944 Avery, Mc Leod, and Mc Carty, cultured S strain and produced cell lysate extract (cell-free extract) and then lipids, proteins and polysaccharides were removed, the streptococcus still retained its ability to replicate its DNA and introduce it into pneumococcus R. Griffith heat inactivation would have left the DNA of the bacteria chromosomes intact, which was the cause of formation of the S gene, and could be released by the destroyed cells and implanted in successive cultures of R Strain.
scotland’s isle of skye is a beautiful place to wander, with a ton of land and water wildlife to enjoy. which animal did we say you’ll become most familiar with during your visit?
The isle of Skye in Scotland is a lovely spot to explore and is home to a variety of land and aquatic animals. During your tour, you become most familiar with midges.
The Isle of Skye is well known for its wild landscape, ancient castles, quaint fishing towns, and spectacular views.
Scotland's northwest coast is connected to Skye, the largest island in the Inner Hebrides, by the Skye Bridge and the Malaig Armadale ferry.
There is no such thing as a midge-free area on Skye! Depending on the time of day and the weather, midges emerge between May and September and then disappear.
In the early morning and late at night, they are more frequent. Even when there is no wind or cloud cover, they are still present.
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Complete Question :-
Scotland’s Isle of Skye is a beautiful place to wander, with a ton of land and water wildlife to enjoy. Which animal did we say you’ll become most familiar with during your visit?
1. ospreys
2. puffin
3. seals
4. midges
All of the following are stressors of captive animals except __________: a) residues from their own feces and urine.
b) environments over which they have no control.
c) abnormaly noisy surroundings.
d) none of the given answers.
e) unfamiliar surroundings.
All of the following are stressors of captive animals except d) none of the given answers.
The statement is suggesting that all of the provided options are stressors of captive animals. However, the correct answer is d) none of the given answers. The term "stressor" refers to any factor or condition that can cause stress or disrupt the normal functioning of an organism. While options a, b, c, and e can indeed be stressors for captive animals, it is important to note that these stressors are not exhaustive. There can be other factors such as limited space, social isolation, lack of enrichment, presence of predators, and disruptions in the circadian rhythm, among others, that can also contribute to stress in captive animals. Therefore, it is incorrect to say that only the provided options are stressors and that there are no other potential stressors for captive animals.
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Match the following terms with the correct definition. Arterioles Arteries Capillaries Venules Veins Small vessels that carry blood away from the heart to the capillaries are __________. Muscular-walled vessels that carry blood away from the heart are _______. One-cell-thick microscopic vessels that function to exchange nutrients and wastes are _________. Small vessels that connect to the capillaries that carry blood back to the heart are ________. Vessels that carry blood back to the heart are _________.
Answer:
Small vessels that carry blood away from the heart to the capillaries are Arterioles. Muscular-walled vessels that carry blood away from the heart are Arteries. One-cell-thick microscopic vessels that function to exchange nutrients and wastes are Capillaries. Small vessels that connect to the capillaries that carry blood back to the heart are Venules. Vessels that carry blood back to the heart are Veins.
Explanation:
We have different types of vessels in our bodies. We can divide them by their size and structure. Starting from the ones that carry blood away from the heath, we have the arteries. Arteries are vessels of big diameter that have muscle around them. Then, the arteries branch into arterioles, which have a smaller diameter. The arterioles branch into capillaries. These are small vessels with thin walls that allow the exchange of nutrients, wastes, and gases with the neighboring tissues. Once that the blood flows through the capillaries, it goes to the venules, which are small veins that will carry the blood to the veins and these to the heart. The veins do not have muscles in their structures, and their walls are thinner than the ones in the arteries.
how would we know if a fossil was that of a eutherian mammal? a.all teeth except for the molars are replaced
Therian mammals, including marsupials and eutherians, may be identified and discriminated by the quantity, form, and replacement pattern of their teeth.
However, some early Mesozoic fossils with therian characteristics have been discovered in Mongolia, and these cannot be definitively assigned to one of the groups;
that is, we do not know which group of therian mammals they belong to, or whether they belong to another closely related group that has since become extinct.
The infant molars are replaced by teeth known as premolars (also known as bicuspids). A whole adult dentition consists of 32 teeth, 16 on top and 16 on bottom.
The primary dentition is replaced by permanent central incisors, lateral incisors, canines, and first and second premolars. The permanent premolars replace the primary molars, and the permanent molars erupt posterior to those.
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which of the following is not a way in which an enzyme can speed up the reaction that it catalyzes?
a) A shape change of the active site occurs when the substrate binds and enables the reaction.
b) An active site puts the substrates in the positions that favor the reaction.
c) Entering an active site brings substrates in close physical proximity.
d) Active sites of some enzymes attract water, keeping it in the reaction.
e) They lower the activation energy.
d) Active sites of some enzymes attract water, keeping it in the reaction. The substrate is a molecule that fits into a specific area on each enzyme molecule known as the active site.
The active site can generate heat from the surrounding area, increasing the substrate's energy content. The environment cannot be heated by an enzyme to hasten a process. Our bodies include enzymes that act as catalysts to quicken reactions by reducing the activation energy required to initiate a reaction. By reducing the activation energy, enzyme quickens the reaction. The difference between the reactants' and the transition state's free energies is known as activation energy. Enzymes reduce activation energy and traverse the transition state to finish a reaction.
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100 PTS and BRAINLIEST ANSWER FAST
Crops gain genetic diversity when large swathes of farmland are planted with the same crop. Which part of this statement is false?
Farmland is planted with the same crop.
Crops that are the same gain diversity.
Crops are planted in large swathes.
Crops are planted in farmland.
Answer:
the answer is farmland is planted with the same crops
write difference between aerobic and anaerobic repiration?
Explanation:
Aerobic respiration takes place in the mitochondria and requires oxygen and glucose, and produces carbon dioxide, water, and energy.
Anaerobic respiration also produces energy and uses glucose, but it produces less energy and does not require oxygen
In terrestrial plants, the closing of stomates to reduce water loss when water is scarce has two major trade-offs: photosynthesis is limited due to _______, and membranes can be damaged by _______. a. limited CO2 uptake; energy accumulation b. increased retention of H2O; energy accumulation c. limited CO2 uptake; an increase in enzyme concentrations d. limited retention of H2O; increased transpiration
The right response is (a) limited energy accumulation; limited CO2 uptake. Stomates close to lessen water evaporation, which also lessens CO2 uptake, which is important for photosynthesis to take place.
The rate of photosynthesis is hence constrained. Moreover, when stomates close, the chloroplasts may accumulate energy in the form of extra electrons and light energy, which may harm the photosynthetic membranes. Reactive oxygen species production and excessive electron transport chain decrease are two factors that might lead to this harm. Terrestrial plants are plants that live on land, as opposed to aquatic or marine plants. They are adapted to grow in soil and to obtain their nutrients and water from the soil, rather than from the surrounding water. Terrestrial plants have a number of adaptations that allow them to survive in their environments, such as the development of roots, stems, and leaves, the ability to store water, and the ability to reproduce in dry conditions. Examples of terrestrial plants include trees, grasses, shrubs, and flowering plants.
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What is Limestone (CaCO3 Calcium Carbonate)?
A: Cryptocrystalline quartz on the ocean floor
B: An ocean lava that creates islands
C: An ocean sedimentary rock formed from the shells of dead organisms
D: A clastic sedimentary rock deposited into the ocean from rivers
Answer:
C: An ocean sedimentary rock formed from the dhells of dead organisms
Answer:
C
Explanation:
Limestone, otherwise known as Calcium Carbonate, is an ocean sedimentary rock formed from the shells of dead organisms.
When these animals die, their shell and skeletal debris accumulate as a sediment that might be lithified into limestone. Limestones formed from this type of sediment are biological sedimentary rocks.
The mitochondria is a part of both the animal and plant cells.
Answer:
True
Explanation:
It is the powerhouse of every cell :)
Answer:
Both animal and plant cells have a mitochondria.
What would be the physiological explanation for why urine volume might increase after drinking water?
Drinking more water causes excess fluid content in the blood that will be eliminated in the form of urine.
Water is absorbed in the various parts of the digestive system into the blood. This fluid in the blood is further reabsorbed by the kidneys in the structures called nephrons. These nephrons filter the blood leaving away the molecules which are larger and of higher atomic weight.
The filtrate formed by the nephrons is known as glomerular filtrate and this passes on from the kidney to the urinary bladder. The filtrate consists of water along with wastes and salts from the blood. Thus, kidneys purify the blood and the urinary bladder lets it out through urination.
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Question- Do you get it?
What happens during Anaphase I?
A. Tetrads line up down the middle of the cell!
B. Chromatin condenses to form visible chromosomes!
C. Homologous chromosomes separate and move toward opposite ends of the cell!
D. All of the above.
A
C
Answer:
Separation of homologous chromosomes occurs after the formation of tetrads, during anaphase I of meiosis. ... Both divisions require the condensation of chromosomes and eventual cytokinesis to produce daughter cells. Sister chromatids are separated during anaphase of mitosis, and during anaphase II of meiosis.
Translation is the
part of the central dogma of molecular
biology.
a RNA to DNA
b DNA to Proteins
C DNA to RNA
d RNA to protein
TRUE/FALSE. prokaryotic gene regulation is geared toward responding to changes in the ; in multicellular eukaryotes, gene regulation is critical for directing and maintaining .
Prokaryotic gene regulation is geared toward responding to changes in the environment; in multicellular eukaryotes, gene regulation is critical for directing development and maintaining homeostasis.
The body's capacity to keep a number of functions and values that are essential to our survival constant is known as homeostasis. Cellular control is crucial for accomplishing this. By controlling the mechanisms that maintain the environment's homeostasis, regulation enables humans to react quickly to environmental changes.
Another mechanism via which the body maintains homeostasis is gene regulation or expression. For instance, the gene encoding a particular enzyme may become active in the presence of excessive substrate, resulting in the production of the enzyme and restoring substrate levels to normal.
Conversely, if the body notices that the levels of a substrate may be too low, any genes that might consume that substrate may have their expression silenced, maintaining a balanced level.
The complete question is:
Prokaryotic gene regulation is geared toward responding to changes in the_________; in multicellular eukaryotes, gene regulation is critical for directing __________ and maintaining ___________.
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